Shroom Your Way to Wellness


On my instagram, I talked about 5 functional mushrooms that can be used for specific wellness needs. So, I won't talk about those again. There are a bunch more functional mushrooms out there that are super exciting and can be used for cooking in functional recipes or as supplements to meet your wellness goals. Without further ado, let's do part dos of functional mushrooms with 5 more shrooms.



Studies show that this mushroom has pretty great potential for modulating the immune system and can act adjunctively with cancer and HIV treatments. This particular mushroom has anti-tumor and immune-modulating properties due to the glucans found in them. Studies are particularly focused on a certain fraction of Maitake called the D-fraction since it has higher amounts of these glucans. There is some evidence that Maitake could be beneficial for diabetes and high blood pressure also.



Mesima is a mushroom found in the cloudy forests of Eastern Asia. Studies show that this functional fungus is liver-protective; increases the effectiveness chemotherapeutic drugs to fight cancer (5-FU); has anticancer effects for a variety of cancer lines by inhibiting the growth of cancer cells and causing cell death; increases immune function against infections; inhibit the development of Type I Diabetes by modulating the immune system; and acts as an anti-inflammatory. Mesima sounds pretty awesome, now that I'm thinking about it.



Much like the two above, Agarikon has been shown to have anti-tumor properties. But, to stay unique from the above, this functional shroom also has cosmetic powers. A study showed that when agarikon powder was combined with cosmetics, it reduced the appearance of shininess and skin imperfections.



Yeah, this one modulates the immune system too. But, this one is a cool one. There's a component in it called active hexose correlated compound (AHCC), which is basically a type of sugar-protein, that helps with the prognosis of colorectal cancers and hepatocellular carcinomas. It should be noted though that AHCC was taken in conjunction with standard chemotherapy to show better survival rates for early-stage gastric cancers compared to those taking AHCC + chemotherapy with later-stage gastric cancers. Shiitake also shows great anti-viral potential (with studies showing that it increases the effectiveness of antiretroviral treatment for HIV) and great antibacterial potential (with research revealing that it inhibits the growth of Staph aureus and E. coli).



This functional fungus has shown great antibacterial activity and antioxidant properties. Enoki has also shown potential to be neuroprotective in pheochromocytoma cells and showed potential to impact allergic airway disease in animal models. Research also shows that this mushroom has the potential to reduce total cholesterol, LDL cholesterol, LDL/HDL ratio, and triglycerides in animal models.


Shrooms Recap

All of the mushrooms above show immunomodulating properties, with effect on cancers, tumors, and some infections. Some of these mushrooms have more advantages to them, which means you can pick and choose your mushrooms to target your wellness goals. Again, as I said in my instagram post, make sure that you either cook these functional mushrooms or get supplements that are heat-treated so that your body can fully access the nutrients in each of these mushrooms. So, have fun shrooming with these functional mushrooms - you have 5 more to add to the 5 that I talked about before. I'm going to try and figure out ways to incorporate functional fungi into some recipes and share them with y'all when I find the best combo.


Comment below if you've tried any of these mushrooms or any other functional mushrooms before. Also, comment below if you've tried using functional mushrooms in recipes.

- Dr. B





Alonso, Eliana Noelia, et al. “Antitumoral Effects of D-Fraction from Grifola Frondosa (Maitake) Mushroom in Breast Cancer.” Nutrition and Cancer, vol. 69, no. 1, 2016, pp. 29–43., doi:10.1080/01635581.2017.1247891

Chu, Po-Yu, et al. “Oral Fungal Immunomodulatory Protein- Flammulina Velutipes Has Influence on Pulmonary Inflammatory Process and Potential Treatment for Allergic Airway Disease: A Mouse Model.” Journal of Microbiology, Immunology and Infection, vol. 50, no. 3, 2017, pp. 297–306., doi:10.1016/j.jmii.2015.07.013.

Dong, Ya-Ru, et al. “Antimicrobial and Antioxidant Activities of Flammulina Velutipes Polysacchrides and Polysacchride-Iron(III) Complex.” Carbohydrate Polymers, vol. 161, 2017, pp. 26–32., doi:10.1016/j.carbpol.2016.12.069.

Finimundy, Tiane Cristine, et al. “A Review on General Nutritional Compounds and Pharmacological Properties of the ≪i≫Lentinula Edodes≪/i≫ Mushroom.” Food and Nutrition Sciences, vol. 05, no. 12, 2014, pp. 1095–1105., doi:10.4236/fns.2014.512119.

Freilich, Drew, et al. “Possible Chemosensitizing and Potent Anticancer Effects of D-Fraction in Combination with Vitamin C on Three Prevalent Urologic Cancer Cells.” Journal of Cancer Therapy, vol. 05, no. 14, 2014, pp. 1402–1411., doi:10.4236/jct.2014.514142.

Hsieh, Pei-Wen, et al. “Chemistry and Biology of Phellinus Linteus.” BioMedicine, vol. 3, no. 3, 2013, pp. 106–113., doi:10.1016/j.biomed.2013.01.002.

Hu, Mingdong, et al. “Extraction of Polysaccharides from Fomes Officinalis Ames and Their Antitumor Activity.” Experimental and Therapeutic Medicine, vol. 6, no. 2, 2013, pp. 451–454., doi:10.3892/etm.2013.1163.

Hu, Qiuhui, et al. “Identification of Flavonoids from Flammulina Velutipes and Its Neuroprotective Effect on Pheochromocytoma-12 Cells.” Food Chemistry, vol. 204, 2016, pp. 274–282., doi:10.1016/j.foodchem.2016.02.138.

Kawaguchi, Yusai. “Active Hexose Correlated Compound (AHCC) and Immune Outcomes in Humans: A Review.” Natural Medicine Journal, Sept. 2009, 

Konno, Sensuke, et al. “Potent Anticancer Effects of Bioactive Mushroom Extracts (Phellinus Linteus) on a Variety of Human Cancer Cells.” Journal of Clinical Medicine Research, vol. 7, no. 2, 2015, pp. 76–82., doi:10.14740/jocmr1996w.

Nanba, Hiroaki, et al. “Effects of Maitake (Grifola Frondosa) Glucan in HIV-Infected Patients.” Mycoscience, vol. 41, no. 4, 2000, pp. 293–295., doi:10.1007/bf02463941.

Shiow-Chyn, H, et al. “Hepatoprotective Principles and Other Chemical Constituents from the Mycelium of Phellinus Linteus.” 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), 2017, doi:10.1055/s-0037-1608105

Wu, Shu-Jing, et al. “Phellinus Linteus Polysaccharides and Their Immunomodulatory Properties in Human Monocytic Cells.” Journal of Functional Foods, vol. 5, no. 2, 2013, pp. 679–688., doi:10.1016/j.jff.2013.01.011.

Wu, Yuanzheng, et al. “Mushroom Cosmetics: The Present and Future.” Cosmetics, vol. 3, no. 3, Aug. 2016, p. 22., doi:10.3390/cosmetics3030022.

Xiao, Chun, et al. “Hypoglycemic Effects of Grifola Frondosa (Maitake) Polysaccharides F2 and F3 through Improvement of Insulin Resistance in Diabetic Rats.” Food Funct., vol. 6, no. 11, 2015, pp. 3567–3575., doi:10.1039/c5fo00497g.

Yahaya, Noor Fazila Mohamed, et al. “Therapeutic Potential of Mushrooms in Preventing and Ameliorating Hypertension.” Trends in Food Science & Technology, vol. 39, no. 2, 2014, pp. 104–115., doi:10.1016/j.tifs.2014.06.002.

Yeh, Ming-Yei, et al. “Hypolipidemic and Antioxidant Activity of Enoki Mushrooms (Flammulina Velutipes).” BioMed Research International, vol. 2014, 2014, pp. 1–6., doi:10.1155/2014/352385


DISCLAIMER: These statements have not been evaluated by the Food and Drug Administration. There are no financial ties to any supplement companies, pharmaceutical companies, or to any of the products mentioned in this post. This post is not meant to treat, cure, prevent, or diagnose conditions or diseases and is meant for educational purposes. As always, please consult your doctor before trying any new treatments or supplements.


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